Education

THC and CBD: understanding the difference

THC and CBD are the two most-studied compounds in cannabis. Here's what sets them apart and why the ratio matters.

Illustrated clinical comparison of THC and CBD around the human body

Cannabis contains dozens of active compounds called cannabinoids. The two most studied are THC and CBD. Understanding their difference helps explain why a practitioner chooses a specific product and ratio.

THC

THC (tetrahydrocannabinol) is responsible for cannabis's psychoactive effect — the feeling of being 'high'. In a medical context it's often associated with managing pain, nausea and appetite. Because it's intoxicating, it calls for careful dosing, especially at first.

CBD

CBD (cannabidiol) is non-intoxicating: it doesn't produce a high. It's studied notably for anxiety, inflammation and sleep. Many patients prefer a CBD-rich ratio when they want to limit psychoactive effects.

Do you need a prescription for CBD oil in Canada?

CBD is regulated as cannabis, including when it comes from hemp. An adult may legally buy a cannabis oil containing CBD from a provincially authorized retailer. For medical access, a practitioner instead provides a medical document — often called a prescription in everyday language — that lets the patient register with a federally licensed seller. These cannabis products are not automatically approved prescription drugs with a drug identification number; that is a distinct regulatory category.

The THC:CBD ratio

Most treatment plans combine the two in a ratio chosen by the practitioner based on your goals and tolerance. There's no universal dose: you generally start low and adjust gradually, with follow-up.

This content is provided for information to adults of legal age only and is not medical advice. Medical cannabis is not a first-line treatment and is not right for everyone. Coverleaf does not diagnose and does not guarantee a prescription. In an emergency, call 911.
Frequently asked
Does CBD make you high?
No, CBD is non-intoxicating. Only THC produces the psychoactive effect.
Can I obtain CBD oil with a medical document?
Yes. When a practitioner considers medical access appropriate, the medical document lets you register with a Health Canada–licensed seller and choose a legal product containing CBD. Neither the document nor a product is guaranteed, and medical cannabis products are not interchangeable with approved prescription drugs.
Which ratio is right for me?
It depends on your situation and is decided with a practitioner. There's no universal answer.
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General information, not medical advice. Coverleaf does not guarantee a prescription or coverage. For adults of legal age. In an emergency, call 911.